Synthesis and materialization of a reaction–diffusion French flag pattern

[PDF]

Synthesis and materialization of a reaction-diffusion

DNA-based reaction networks to synthesize a French flag, an archetypal pattern composed of three chemically distinct zones with sharp borders whose synthetic analogue has remained elusive. A bistable network within a shallow concentration gradient creates an immobile, sharp and long-lasting concentration front through a reaction–diffusion mechanism.

Synthesis and materialization of a reaction–diffusion

A DNA-based reaction network has now been developed that creates a French flag pattern with immobile and sharp borders from a shallow initial concentration gradient. The output pattern …

Synthesis and materialization of a reaction-diffusion

Second, these concentration patterns control the macroscopic organization of DNA-decorated particles, inducing a French flag pattern of colloidal aggregation. This experimental framework could be used to test reaction-diffusion models and fabricate soft materials following an …

Synthesis and materialization of a reaction-diffusion

through a reaction-diffusion (RD) mechanism, progressively decelerating until it stopped at the center of the channel at a position where RRD 1 = 30 5 nM. The characteristic width of the front was 2 mm, 10-fold sharper than the morphogen gradient, and remained immobile up to 15 h (Extended Data Figure 4b).

[1701.06527] Synthesis and materialization of a reaction

The archetypal pattern is the French flag composed of three chemically-distinct zones separated by sharp borders. Chemical concentration serves the underlying cells both as an indicator of …

Synthesis and materialization of a reaction-diffusion

The archetypal pattern is the French flag composed of three chemically-distinct zones separated by sharp borders.

Synthesis and materialization of a reaction-diffusion

During embryo development, patterns of protein concentration appear in response to morphogen gradients. The archetypal pattern is the French flag composed of three chemically-distinct zones separated by sharp borders. Chemical concentration serves the underlying cells both as an indicator of location and as a fate selector.

Patterning World Flags and More with DNA – Chembites

Figure 1: The Polish flag experiment gave a distinct concentration split between blue and red labeled DNA, controlled by a template strand TH, which forms the …

Pursuit-and-Evasion Reaction-Diffusion Waves in

However, in addition to the intrinsic chemical parameters, initial and boundary conditions have a major impact on the final structure. Here we take advantage of microfluidics to design controlled reactors and investigate pursuit-and-evasion chemical waves generated by a DNA-based reaction network with Predator–Prey dynamics.