Sep 21, 2016 · See letter «Letter to the Editor regarding ‘Treatment of Men for “Low Testosterone”: A Systematic Review’ by Huo et al.; Testosterone Replacement Therapy: Toward to the Robust Evidence and Facts» in World J Mens Health, volume 34 on page 224.
We performed a systematic review of 156 eligible randomized controlled trials in which testosterone was compared to placebo for one or more of these conditions.
a variety of symptoms identified as those of “low testosterone” (low-T), a term that has not been uniformly defined. We present a systematic review of randomized controlled trials (RCTs) that evaluated the use of testosterone therapy against placebo or inactive comparator in
We present a systematic review of randomized controlled trials (RCTs) that evaluated the use of testosterone therapy against placebo or inactive comparator in adult men for cardiovascular health, sexual function, muscle weakness/wasting, mood and behavior, or cognition.
This review was registered a priori (CRD42014009963) and followed the Cochrane handbook18 and the PRISMA for Network Meta-Analysis checklist.19 Our review included RCTs and NRS involving adult men with low testosterone taking any form of TRT compared with placebo, another TRT, or the same TRT at a different dose. We did not exclude studies on the basis of reported outcomes.
In men, testosterone treatment is a controversial alternative or adjunct treatment option. Huo S, Scialli AR, McGarvey S, et al. Treatment of men for “low testosterone”: a systematic review. PLoS One. 2016;11(9):e0162480
The use of testosterone replacement therapy (TRT) for men has risen dramatically in recent years. This comprehensive review article covers many aspects of TRT, including testosterone metabolism, indications for TRT, diagnostic testing with a decision-to-treat algorithm, contraindications, and risks vs benefits of treatment.
Sep 20, 2016 · Physicians diagnose and treat suspected hypogonadism in older men by extrapolating from the defined clinical entity of hypogonadism found in younger men. We conducted a systematic review to estimate the accuracy of clinical symptoms and signs for predicting low testosterone among aging men.
Nov 15, 2018 · Now a new, systematic review and meta-analysis of the research in JAMA Psychiatry suggests that the evidence supports using testosterone treatments for depression in men …
In this systematic review, we identified seven observational studies and eight RCTs pertaining to the cerebrovascular safety of testosterone in men. Two large observational studies observed a decreased risk of stroke associated with TRT in hypogonadal men, whereas the remainder did not formally evaluate this specific relationship.
We conducted a systematic review to estimate the accuracy of clinical symptoms and signs for predicting low testosterone among aging men. Methods: We searched the MEDLINE and Embase databases (January 1966 to July 2014) for studies that compared clinical features with a measurement of serum testosterone in men.